What Is Endometrial Receptivity Analysis?

An in vitro fertilisation (IVF) routine aims to accurately time the readiness of the endometrium and the placement of the embryo. Unfortunately, this timing is not always accurate, impairing implantation. That's where endometrial receptivity analysis (ERA) comes in. ERA is a pathbreaking technology that helps embryologists to scientifically determine endometrial preparedness at a nanoscopic level. By performing an embryo transfer during the optimal endometrial window, the chances of implantation rise.

Why Choose Endometrial Receptivity Analysis?

Endometrial receptivity analysis (ERA) is far ahead of other methods of endometrial assessment. Here's how.

Is Endometrial Receptivity Analysis Right for Me?

On Cloudnine, we recommend endometrial receptivity analysis (ERA) for guests who have a history of unsuccessful embryo implantation. Often, despite a spate of agreeable parameters like quality embryos, a healthy uterus and an adequate endometrial thickness, implantation fails to occur due to an ill-timed embryo transfer. ERA is also advisable for guests whose endometrial thickness fluctuates from cycle to cycle, not always touching the 8-millimetre benchmark.

What Are the Steps of Endometrial Receptivity Analysis?

An endometrial receptivity analysis (ERA) involves two main steps, which work in sync to provide insights to your fertility consultant about the health of your endometrium.

  • 1Endometrial Biopsy

    First, an endometrial biopsy is performed by your doctor, between the 19th and 21st day of your menstrual cycle. The routine is conducted using a Pipelle catheter, and is quick and straightforward.

  • 2Gene Sequencing

    Once the biopsy is performed, your doctor will carefully examine the pattern of the 236 genes that play a role in endometrial readiness. A pioneering technology hosted exclusively on Cloudnine then sieves through the data to recognise whether the endometrium is receptive or not. Based on the output, your fertility consultant will discuss a treatment route with you.

What Are the Risks of Endometrial Receptivity Analysis?

The risks associated with endometrial receptivity analysis (ERA) are few and far between. Risks, if any, could be environmental, or posed by the procedures related to ERA.

Endometrial receptivity analysis

Typically, a lack of synchronization between the embryo and endometrial receptivity is one of the main reasons for recurring implantation failure. Cloudnine provides a complete endometrial receptivity analysis and monitors healthy embryo. It increases the chance of pregnancy

Embryo implantation

The embryo is the earliest promise of a new child. The embryo's potential for pregnancy is expressed when it implants, forming an attachment to its birth mother and building the placenta, with the support and nutrition that are critical to a healthy pregnancy. Without implantation, the embryo won't reach its potential. The efficiency of implantation is another important predictor of pregnancy rates. A highly efficient endometrium allows healthy