The genetic makeup of sperm can play a considerable role in determining the chances of fertilisation and healthy embryo development. Sperm sometimes display traits of DNA fragmentation, potentially pointing to infertility, recurrent miscarriages or IVF Failure.
On Cloudnine Fertility, we perform the sperm chromatin dispersion test to gauge the degree of DNA fragmentation. This evaluation checks whether sperm cells produce a halo of dispersed DNA loops, following acid denaturation and nuclear protein removal. The absence of these loops implies DNA fragmentation. DNA fragmentation can be overcome by extracting sperm directly from the testicles with a needle.
Sperm DNA fragmentation can make conception difficult for couples who want to start a family. A definitive diagnosis can give rise to a range of treatment options.
Sperm DNA fragmentation technology can help your doctor determine the best way to treat your condition. More severe forms of the condition may warrant a longer sequence of procedures, whereas milder forms may require fewer steps.